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Transgenic animals (salmon, GloFish): uses in research

Also: AquAdvantage salmon, GloFish, GM animals, fluorescent zebrafish

Animals carrying added genes. AquAdvantage salmon grows faster using a growth hormone gene and was the first GM animal approved as food in the US (2015). GloFish are fluorescent pet fish developed from research zebrafish.

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Timeline

  1. 1992 Fast-growing transgenic salmon
  2. 2014 AquAdvantage salmon in aquaculture
  3. 2021 Fluorescent zebrafish lines

Readiness: lab lab studies · prototype demonstrated objects · commercial products or buildings in real use · review summaries of other studies.
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Fluorescent zebrafish lines

Choe and colleagues reviewed transgenic fluorescent zebrafish lines and their impact on biomedical research; such lines are the origin of GloFish pets.

As reported in: Choe, Choi, Kee et al. (2021). Transgenic fluorescent zebrafish lines that have revolutionized biomedical research. Laboratory Animal Research. doi:10.1186/s42826-021-00103-2

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biology

food science

lab food science 1992

Fast-growing transgenic salmon

Du and colleagues showed an "all fish" growth hormone gene construct boosted growth in Atlantic salmon, the basis of AquAdvantage salmon.

Built / tested: transgenic salmon

As reported in: Du, Gong, Fletcher et al. (1992). Growth Enhancement in Transgenic Atlantic Salmon by the Use of an “All Fish” Chimeric Growth Hormone Gene Construct. Nature Biotechnology. doi:10.1038/nbt0292-176

Abstract only

commercial food science 2014

AquAdvantage salmon in aquaculture

Clifford described AquAdvantage salmon as a pioneering biotechnology application in fish farming.

Built / tested: AquAdvantage salmon

As reported in: Clifford (2014). AquAdvantage® Salmon - a pioneering application of biotechnology in aquaculture. BMC Proceedings. doi:10.1186/1753-6561-8-s4-o31

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