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Synchrotron light sources: uses in research

Also: synchrotron radiation, X-ray free electron laser

Particle accelerators that make extremely bright X-rays for studying materials and molecules.

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Timeline

  1. 1999 Holotomography
  2. 2005 Synchrotron sources review
  3. 2017 Serial crystallography at a synchrotron

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Synchrotron sources review

Bilderback and colleagues reviewed third- and next-generation synchrotron light sources and X-ray free-electron lasers.

As reported in: Bilderback, Elleaume, Weckert (2005). Review of third and next generation synchrotron light sources. Journal of Physics B: Atomic, Molecular and Optical Physics. doi:10.1088/0953-4075/38/9/022

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physics

lab physics 1999

Holotomography

Cloetens and colleagues combined synchrotron X-ray phase images taken at several distances to map 3D density at micrometer resolution.

As reported in: Cloetens, Ludwig, Baruchel et al. (1999). Holotomography: Quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays. Applied Physics Letters. doi:10.1063/1.125225

Abstract only

structural biology

lab structural biology 2017

Serial crystallography at a synchrotron

Martin-Garcia and colleagues collected room-temperature data from 5–20 µm protein microcrystals at the Advanced Photon Source and solved four structures.

As reported in: Martin-Garcia, Conrad, Nelson et al. (2017). Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation. IUCrJ. doi:10.1107/s205225251700570x

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