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Deer antler regeneration

Regeneration: basic research on living systems, not technology.

Deer regrow their antlers every year, among the fastest-growing tissues in mammals.

Known properties: Deer antler regeneration

Only what the cited papers report.

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Timeline

  1. 2019 Genes for fast antler regrowthCharacterizing antler stem cells
  2. 2023 Antler blastema stem cells

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lab biology 2019

Genes for fast antler regrowth

Wang and colleagues studied ruminant headgear genomes and found selection on cancer-related genes that may function in deer antler development.

As reported in: Wang, Zhang, Wang et al. (2019). Genetic basis of ruminant headgear and rapid antler regeneration. Science. doi:10.1126/science.aav6335

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lab biology 2023

Antler blastema stem cells

Qin and colleagues built a single-cell atlas of antler regrowth and identified antler blastema progenitor cells with strong self-renewal.

As reported in: Qin, Zhang, Zheng et al. (2023). A population of stem cells with strong regenerative potential discovered in deer antlers. Science. doi:10.1126/science.add0488

Abstract only

lab biology 2019

Characterizing antler stem cells

Wang and colleagues found antler stem cells carry classic mesenchymal stem cell markers plus some embryonic stem cell markers.

As reported in: Wang, Berg, Ba et al. (2019). Deer antler stem cells are a novel type of cells that sustain full regeneration of a mammalian organ—deer antler. Cell Death & Disease. doi:10.1038/s41419-019-1686-y

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